Help to Reduce the Risk of Alzheimer’s Disease

 

Many people worry about getting Alzheimer’s disease. Alzheimer’s disease is a form of senile dementia that occurs late in life. But it is not an inevitable part of aging. The brain can keep functioning very well even in people of 100 years or more! Alzheimer’s is a distressing disease for the sufferer and perhaps much more so for family and friends.  There is however nutritional research that shows how you can decrease your likelihood of getting dementia; and to slow the progress of Alzheimer’s.

 

If you have more than one alcoholic drink a day you are likely to be increasing your risk of developing dementia in later life[1, 2]. Some people have a genetic weakness that puts them at risk if they drink any alcohol.

 

But don’t switch to coffee as this can also cause problems when drunk frequently. Both coffee and alcohol increase homocysteine levels in the blood[3]. High homocysteine levels and low levels of the B vitamins[4] have been shown to affect the ability of the brain to function well in older people, if you have high levels of homocysteine you run a high risk of developing dementia[5]. All of the B vitamins are helpful to decrease high homocysteine levels and generally help prevent dementia[3]; especially Folic acid (yes this is a B vitamin), Vitamin B6 and Vitamin B12[3, 4]. You will find these in wholegrains, vegetables and nuts.

 

Teas both green and black, help prevent dementia[6, 7], but don’t have your tea with meals as it can stop your body absorbing important nutrients such as iron.

 

The type of fats you eat can also affect your chances of developing Alzheimer’s. Research shows that polyunsaturated fatty acids are especially important [8-10]. Avoid all processed and overheated fats; instead go for cold pressed oils such as extra virgin olive oil, and plenty of fish[11, 9] and other seafood[11, 12]. This will help provide the helpful fats, seafood and fish are high in omega 3 fatty acids which have been shown to help protect the brain from dementias[12, 10].

 

The way you prepare the fish is also important; baked, boiled or grilled is fine. Definitely avoid deep frying with batter.

The antioxidant vitamin E has been shown to help the brain keep working well in older people[13, 12, 14, 15]. The good quality fats are important to help absorption of vitamin E. You can find vitamin E in nuts, seeds, oils and meats (best organic). Both Garlic[16] and Coenzyme Q10 have also been shown to reduce risk not only of dementia[17-19] but also of cardiovascular disease[20].

 

Sleep, rest and relaxation are important to keep the mind working well. Often fatigue and worry can cause forgetfulness[21, 22]. If you are feeling it is hard to concentrate or are becoming absentminded it does not mean you are getting senile dementia. But when a person has dementia lack of rest will make symptoms worse. Herbal medicine as well as vitamin C and B vitamins[12] can help reduce stress and strengthen the nervous system. I use the Entire Katoa Food State supplements for the best absorption.

 

If you smoke you will be more likely to get dementia so one more reason to make the decision to stop now[23, 24]. Exercise has been shown to reduce the risk of Alzheimer’s by as much as 40%[25, 26]. So be active walk every day breathe in fresh air for a long, happy and interesting life[23].

 

 

 

1.       Lee Y, Back JH, Kim J, Kim SH, Na DL, Cheong HK, Hong CH, Kim YG: Systematic review of health behavioral risks and cognitive health in older adults. Int Psychogeriatr 2010, 22(2):174-187.

 

2.       Zuccalà G, Onder G, Pedone C, Cesari M, Landi F, Bernabei R, Cocchi A: Dose-Related Impact of Alcohol Consumption on Cognitive Function in Advanced Age: Results of a Multicenter Survey. Alcoholism: Clinical and Experimental Research 2001, 25(12):1743-1748.

 

3.       Refsum H, Nurk E, Smith AD, Ueland PM, Gjesdal CG, Bjelland I, Tverdal A, Tell GS, Nygard O, Vollset SE: The Hordaland Homocysteine Study: A Community-Based Study of Homocysteine, Its Determinants, and Associations with Disease. J Nutr 2006, 136(6):1731S-1740.

 

4.       Tucker KL, Qiao N, Scott T, Rosenberg I, Spiro A, III: High homocysteine and low B vitamins predict cognitive decline in aging men: the Veterans Affairs Normative Aging Study. Am J Clin Nutr 2005, 82(3):627-635.

 

5.       Seshadri S, Beiser A, Selhub J, Jacques PF, Rosenberg IH, D'Agostino RB, Wilson PWF, Wolf PA: Plasma Homocysteine as a Risk Factor for Dementia and Alzheimer's Disease. N Engl J Med 2002, 346(7):476-483.

 

6.       Chan YC, Hosoda K, Tsai CJ, Yamamoto S, Wang MF:Favorable effects of tea on reducing the cognitive deficits and brain morphological changes in senescence-accelerated mice. J Nutr Sci Vitaminol (Tokyo) 2006, 52(4):266-273.

 

7.       Ng T-P, Feng L, Niti M, Kua E-H, Yap K-B: Tea consumption and cognitive impairment and decline in older Chinese adults. Am J Clin Nutr 2008, 88(1):224-231.

 

8.       Lukiw WJ, Bazan NG: Docosahexaenoic Acid and the Aging Brain. J Nutr 2008, 138(12):2510-2514.

 

9.       Nurk E, Drevon CA, Refsum H, Solvoll K, Vollset SE, Nygard O, Nygaard HA, Engedal K, Tell GS, Smith AD: Cognitive performance among the elderly and dietary fish intake: the Hordaland Health Study. Am J Clin Nutr 2007, 86(5):1470-1478.

 

10.     Samieri C, Feart C, Letenneur L, Dartigues J-F, Peres K, Auriacombe S, Peuchant E, Delcourt C, Barberger-Gateau P:Low plasma eicosapentaenoic acid and depressive symptomatology are independent predictors of dementia risk. Am J Clin Nutr 2008, 88(3):714-721.

 

11.     Barberger-Gateau P, Letenneur L, Deschamps V, Peres K, Dartigues J-F, Renaud S: Fish, meat, and risk of dementia: cohort study. BMJ 2002, 325(7370):932-933.

 

12.     Morris MC: The role of nutrition in Alzheimer's disease: epidemiological evidence. Eur J Neurol 2009, 16 Suppl 1:1-7.

 

13.     Devore EE, Grodstein F, van Rooij FJ, Hofman A, Stampfer MJ, Witteman JC, Breteler MM: Dietary antioxidants and long-term risk of dementia. Arch Neurol 2010, 67(7):819-825.

 

14.     Morris MC, Evans DA, Bienias JL, Tangney CC, Bennett DA, Aggarwal N, Wilson RS, Scherr PA:Dietary Intake of Antioxidant Nutrients and the Risk of Incident Alzheimer Disease in a Biracial Community Study. JAMA 2002, 287(24):3230-3237.

 

15.     Morris MC, Evans DA, Tangney CC, Bienias JL, Wilson RS, Aggarwal NT, Scherr PA: Relation of the tocopherol forms to incident Alzheimer disease and to cognitive change. Am J Clin Nutr 2005, 81(2):508-514.

 

16.     Borek C: Garlic Reduces Dementia and Heart-Disease Risk. J Nutr 2006, 136(3):810S-812.

 

17.     Beal MF: Mitochondrial Dysfunction and Oxidative Damage in Alzheimer's and Parkinson's Diseases and Coenzyme Q10 as a Potential Treatment. Journal of Bioenergetics and Biomembranes 2004, 36(4):381-386.

 

18.     Isobe C, Abe T, Terayama Y: Increase in the Oxidized/Total Coenzyme Q-10 Ratio in the Cerebrospinal Fluid of Alzheimer’s Disease Patients. Dementia and Geriatric Cognitive Disorders 2009, 28(5):449-454.

 

19.     Ogawa O, Zhu X, Perry G, Smith MA: Mitochondrial Abnormalities and Oxidative Imbalance in Neurodegenerative Disease. Sci Aging Knowl Environ 2002, 2002(41):pe16-.

 

20.     Molyneux S, L., Florkowski C, M. , George P, M. , Pilbrow A, P. , Frampton C, M. , Lever M, Richards AM: Coenzyme Q10: An Independent Predictor of Mortality in Chronic Heart Failure. Journal of the American College of Cardiology 2008, 52(18):1435-1441.

 

21.     Durmer JS, Dinges DF: Neurocognitive Consequences of Sleep Deprivation. Semin Neurol 2005, 25(01):117-129.

 

22.     Thomas M, Sing H, Belenky G, Holcomb H, Mayberg H, Dannals R, JR. HW, Thorne D, Popp K, Rowland L et al:Neural basis of alertness and cognitive performance impairments during sleepiness. I. Effects of 24 h of sleep deprivation on waking human regional brain activity. Journal of Sleep Research 2008, 9(4):335-352.

 

23.     Huang CQ, Dong BR, Zhang YL, Wu HM, Liu QX: Association of cognitive impairment with smoking, alcohol consumption, tea consumption, and exercise among Chinese nonagenarians/centenarians. Cogn Behav Neurol 2009, 22(3):190-196.

 

24.     Reitz C, den Heijer T, van Duijn C, Hofman A, Breteler MMB: Relation between smoking and risk of dementia and Alzheimer disease: The Rotterdam Study. Neurology 2007, 69(10):998-1005.

25.     Larson EB, Wang L, Bowen JD, McCormick WC, Teri L, Crane P, Kukull W: Exercise Is Associated with Reduced Risk for Incident Dementia among Persons 65 Years of Age and Older. Annals of Internal Medicine 2006, 144(2):73-81.

 

26.     Laurin D, Verreault R, Lindsay J, MacPherson K, Rockwood K: Physical Activity and Risk of Cognitive Impairment and Dementia in Elderly Persons. Arch Neurol 2001, 58(3):498-504.

 

 


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